Batch documentation
Certificate of analysis
Apex Laboratory results for the listed configurations. Match the lot on your label with the report.
Cagrisema (2.5 mg+2.5 mg)
- Cagrilintide chromatographic purity
- 99.946 % integrated detector area
- Semaglutide chromatographic purity
- 99.854 % integrated detector area
- Cagrilintide active content
- 2.50287 mg/vial
- Semaglutide active content
- 2.50685 mg/vial
Chromatographic purity by analyte
About this graph
Recorded scalar results against the stated specification. Each row uses its own labeled scale; purity is detector-area purity, not active-material content.
Measured active content
About this graph
Calibrated active content, concentration or activity compared with the stated same-unit specification. Each row uses its own labeled scale; no conversion from chromatographic purity is made.
Cagrisema (2.5mg+2.5mg) is a dual amylin/glp-1 combination supplied by Apex Laboratory as a high-purity research peptide intended strictly for in-vitro laboratory research and development applications.
Compound Overview
CagriSema combines Cagrilintide (an amylin receptor agonist) with Semaglutide (a GLP-1 receptor agonist) to enable research into dual-pathway metabolic signaling. This combination targets amylin receptors and GLP-1 receptors simultaneously, two complementary pathways involved in appetite regulation and metabolic homeostasis.
Research Background & Published Literature
Frias and colleagues studied co-administered clinical cagrilintide and semaglutide in adults with type 2 diabetes. Its clinical formulations and protocol are distinct from a fixed research blend labeled 2.5 mg + 2.5 mg. The trial does not establish blend homogeneity, stability, delivered content or clinical equivalence for the product listed here.
Researchers interested in the published literature surrounding this compound can explore the following peer-reviewed resources for additional context on its mechanism of action, signaling pathways, and experimental applications in controlled laboratory settings:
Technical Specifications
- Product Name: Cagrisema (2.5mg+2.5mg)
- Classification: Dual Amylin/GLP-1 Combination
- Structural Description: Fixed-dose combination of Cagrilintide (amylin analog) and Semaglutide (GLP-1 agonist)
- Molecular Weight: Cagrilintide: 3976.6 g/mol + Semaglutide: 4113.58 g/mol
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
Storage, Handling & Stability Guidelines
Store lyophilized at -20°C. Reconstituted at 2–8°C, use within 14 days.
- Minimize time at ambient temperature during handling to preserve compound integrity.
- Avoid moisture exposure by resealing vials promptly after each withdrawal.
- Use appropriate personal protective equipment and follow your institution’s chemical safety protocols at all times.
- Label all aliquots with the compound name, concentration, date of reconstitution, and operator initials for complete traceability.
Quality Assurance & Analytical Verification
Review the tests recorded for the applicable configuration and lot. The published Apex Laboratory record identifies the issuer, methods, results, units and acceptance criteria. A public configuration record does not by itself identify the lot currently shipping or establish independent accreditation.
Frequently Asked Questions
What is the composition of CagriSema?
CagriSema contains Cagrilintide 2.5mg (amylin analog, CAS 2375301-38-9) and Semaglutide 2.5mg (GLP-1 agonist, CAS 910463-68-2) in a single lyophilized vial for dual-pathway research.
Why combine Cagrilintide and Semaglutide?
The combination allows researchers to study how concurrent amylin receptor and GLP-1 receptor activation interact, targeting two complementary metabolic signaling pathways in a single experimental setup.
Is this product approved for human use?
No. All compounds sold by Apex Laboratory are classified as chemical research reagents intended strictly for in-vitro laboratory research. They are not approved for human consumption, veterinary use, or any therapeutic application. Purchasers who imply intended bodily use will have their orders cancelled and accounts permanently suspended.
What documentation is available for this compound?
Open the applicable published configuration and lot record in the COA library. Read its issuer, methods, results, units and reporting limits, and match the complete lot on your material. If a particular lot or additional documentation is required, contact support before ordering; publication alone does not identify the lot that will ship.
Is bulk ordering available?
Yes. For bulk quantities, custom packaging requirements, or recurring supply agreements, contact our team with the compound name, desired quantity, preferred research-material format, and your target delivery timeline. Volume pricing is available for qualifying orders.
Related Research Compounds
Researchers studying dual amylin/glp-1 combination pathways may also be interested in related compounds available from Apex Laboratory, including Cagrilintide, Semaglutide, Tirzepatide. Explore our complete research catalog to browse all available peptides, reagents, and laboratory supplies, or visit our About page to learn more about our quality verification process.
Shipping, Packaging & Delivery
Orders with cleared payment before 2:00 PM ET on a business day usually ship the same business day. Payment, address or inventory review and carrier conditions can affect timing. Review the shipping information for handling exceptions and current delivery estimates. Contact support before ordering if your research requires a particular packaging or shipping condition.
Research Use Disclaimer
For in-vitro research use only. Not for human consumption. All products sold by Apex Laboratory are intended exclusively for qualified researchers, accredited laboratories, and educational institutions. Purchasers assume full responsibility for ensuring safe handling, proper storage, and compliance with all applicable federal, state, and local laws, regulations, and institutional policies governing the purchase and use of chemical research reagents.
