Batch documentation
Certificate of analysis
Apex Laboratory results for the listed configurations. Match the lot on your label with the report.
SS-31 - 50 mg
- SS-31 chromatographic purity
- 99.863 % integrated detector area
- SS-31 active content
- 50.1115 mg/vial
- Bacterial endotoxins
- <0.025 EU/mg active-equivalent
- Sterility: FTM
- No growth at 14 days in all 20 units
Chromatographic purity by analyte
About this graph
Recorded scalar results against the stated specification. Each row uses its own labeled scale; purity is detector-area purity, not active-material content.
Measured active content
About this graph
Calibrated active content, concentration or activity compared with the stated same-unit specification. Each row uses its own labeled scale; no conversion from chromatographic purity is made.
SS-31 - 10 mg
- SS-31 chromatographic purity
- 99.869 % integrated detector area
- SS-31 active content
- 10.0023 mg/vial
- Bacterial endotoxins
- <0.025 EU/mg active-equivalent
- Sterility: FTM
- No growth at 14 days in all 20 units
Chromatographic purity by analyte
About this graph
Recorded scalar results against the stated specification. Each row uses its own labeled scale; purity is detector-area purity, not active-material content.
Measured active content
About this graph
Calibrated active content, concentration or activity compared with the stated same-unit specification. Each row uses its own labeled scale; no conversion from chromatographic purity is made.
SS-31 is a mitochondria-targeted antioxidant peptide supplied by Apex Laboratory as a high-purity research peptide intended strictly for in-vitro laboratory research and development applications.
Compound Overview
SS-31, also named elamipretide, is a tetrapeptide investigated in mitochondrial research. Birk and colleagues studied cardiolipin interactions and a rat renal-ischemia model. Interpret those findings within the tested biochemical and animal conditions; they do not establish a universal clinical benefit or the activity of a supplied lot.
Research Background & Published Literature
Szeto reviewed cell-permeable peptide antioxidants targeted to mitochondria. Read the individual experimental models and compound structures before transferring a finding between peptides. This research context does not establish a clinical effect or validate the identity of a supplied SS-31 lot.
Birk and colleagues studied SS-31/cardiolipin interactions and a rat renal-ischemia model. Their biochemical and animal findings concern those tested conditions. Clinical elamipretide studies use specified formulations and populations; they do not validate this research vial or prove a universal cardiac benefit.
In PROGRESS-HF, elamipretide did not improve left-ventricular end-systolic volume at four weeks compared with placebo in the studied heart-failure population. Clinical formulations and populations are separate from this research-use vial. Read the PROGRESS-HF primary report and SS-31 evidence guide for the trial and formulation distinctions.
Researchers interested in the published literature surrounding this compound can explore the following peer-reviewed resources for additional context on its mechanism of action, signaling pathways, and experimental applications in controlled laboratory settings:
- Szeto (2006) — review of mitochondrial-targeted peptide antioxidants
- Birk et al. (2013) — cardiolipin interaction and rat renal-ischemia experiments
Technical Specifications
- Product Name: SS-31
- Classification: Mitochondria-Targeted Antioxidant Peptide
- Structural Description: 4-amino acid peptide (D-Arg-Dmt-Lys-Phe-NH2), also known as Elamipretide/Bendavia
- CAS Number: 736992-21-5
- Molecular Weight: 639.8 g/mol (neutral elamipretide peptide)
- Purity: ≥99% (verified by HPLC and Mass Spectrometry)
- Physical Form: Lyophilized (freeze-dried) powder
- Intended Use: In-vitro research use only — not for human consumption
Storage, Handling & Stability Guidelines
Store lyophilized material at -20°C for long-term stability. After reconstitution with sterile diluent, refrigerate at 2–8°C and minimize freeze-thaw cycles by aliquoting working volumes according to your standard operating procedures.
- Minimize time at ambient temperature during handling to preserve compound integrity.
- Avoid moisture exposure by resealing vials promptly after each withdrawal.
- Use appropriate personal protective equipment and follow your institution’s chemical safety protocols at all times.
- Label all aliquots with the compound name, concentration, date of reconstitution, and operator initials for complete traceability.
Quality Assurance & Analytical Verification
Review the tests recorded for the applicable configuration and lot. The published Apex Laboratory record identifies the issuer, methods, results, units and acceptance criteria. A public configuration record does not by itself identify the lot currently shipping or establish independent accreditation.
Frequently Asked Questions
What is the primary research application of this compound?
This compound is classified as a mitochondria-targeted antioxidant peptide and is used in laboratory settings to study related signaling pathways and biological mechanisms in controlled in-vitro experiments.
What storage conditions are recommended?
For long-term storage, keep the lyophilized material at -20°C in a sealed container away from moisture and light. After reconstitution, refrigerate at 2–8°C and use within the recommended timeframe for your workflow.
Is this product approved for human use?
No. All compounds sold by Apex Laboratory are classified as chemical research reagents intended strictly for in-vitro laboratory research. They are not approved for human consumption, veterinary use, or any therapeutic application. Purchasers who imply intended bodily use will have their orders cancelled and accounts permanently suspended.
What documentation is available for this compound?
Open the applicable published configuration and lot record in the COA library. Read its issuer, methods, results, units and reporting limits, and match the complete lot on your material. If a particular lot or additional documentation is required, contact support before ordering; publication alone does not identify the lot that will ship.
Is bulk ordering available?
Yes. For bulk quantities, custom packaging requirements, or recurring supply agreements, contact our team with the compound name, desired quantity, preferred research-material format, and your target delivery timeline. Volume pricing is available for qualifying orders.
Related Research Compounds
Researchers studying mitochondria-targeted antioxidant peptide pathways may also be interested in related compounds available from Apex Laboratory, including MOTS-c (Human), Humanin 10mg, NAD+. Explore our complete research catalog to browse all available peptides, reagents, and laboratory supplies, or visit our About page to learn more about our quality verification process.
Shipping, Packaging & Delivery
Orders with cleared payment before 2:00 PM ET on a business day usually ship the same business day. Payment, address or inventory review and carrier conditions can affect timing. Review the shipping information for handling exceptions and current delivery estimates. Contact support before ordering if your research requires a particular packaging or shipping condition.
Research Use Disclaimer
For in-vitro research use only. Not for human consumption. All products sold by Apex Laboratory are intended exclusively for qualified researchers, accredited laboratories, and educational institutions. Purchasers assume full responsibility for ensuring safe handling, proper storage, and compliance with all applicable federal, state, and local laws, regulations, and institutional policies governing the purchase and use of chemical research reagents.
